What is Follistatin 344?

Many of us wish that we could impress everyone we meet with our build, having enormous muscles, insane strength, and an overall husky appearance.

We tend to envision having the same figure as our fitness idols and one day surpassing their greatness.

While it isn’t possible for anyone to achieve this feat overnight, dedicated bodybuilders and elite-level athletes spend endless hours on high-intensity workouts and training to turn their dreams into a reality

In order to accelerate and enhance the process, many of these individuals look to the use of natural and synthetic peptides or proteins as they are well-researched and provide a safer alternative to the use of steroids.

One such protein that has great promise is Follistatin 344. Animal-based trials focused on this glycoprotein suggest that it significantly improves muscle growth and provides a realm of secondary benefits.

Stay with me till the end to decide whether or not you should use this glycoprotein as a part of your journey.

I’ll provide all of the facts, research, and personal reviews possible in order to help guide you in the right direction.

I’ll even provide my honest opinion at the end of this thread on Follistatin 344.

What Is Follistatin 344

Follistatin 344 is a recombinant form of naturally occurring follistatin. It comprises 323 Amino acids, and a carbohydrate chain is attached to its core, making it a naturally occurring glycoprotein.

Follistatin is a glycoprotein produced by folliculostellate cells (FS) located in the anterior pituitary gland and follows the autocrine signaling pathway.

Regarding the amino acids that make up follistatin 344, there is unusually high cysteine, a non-essential amino acid. Cysteine gives follistatin 344 its key characteristic property

How Does Follistatin Work

Follistatin 344 follows multiple courses of action to trigger specific changes in the body.

Myostatin, a growth and differentiation factor protein, is produced by myocytes (muscle cells). The primary function of myostatin is to act as a regulator by limiting the growth of muscles so that they don’t grow out of shape.

Follistatin 344 acts as a myostatin inhibitor. This subsequent blocking of myostatin by follistatin 344 leads to the suppression of myostatin activity. Thus, myostatin can’t act as a potent negative regulator of muscle growth.

Activin proteins enhance the secretion of follicle-stimulating hormone (FSH). However, in men, higher levels of follicle-stimulating hormone (FSH) limit muscle growth and cause abnormal testicle functioning.

Follistatin 344 inhibits the activin, which results in decreased secretion of the hormone.

Follistatin 344 acts on the granulosa cells to trigger the release of progesterone.  As progesterone is one of the main hormones regulating the menstrual cycle, slight fluctuations in the hormonal levels can disturb the whole cycle.

Although no human trials have confirmed these results, animal-based studies suggest that follistatin can reduce the life and growth of cancer cells and minimize the chances of metastasis.

Benefits Of Follistatin 344

The benefits of follistatin 344 can easily be predicted once you understand the mechanism of action that follistatin 344 follows.

Follistatin 344 inhibits the activity of myostatin which results in increased growth of muscle fibers in the body. Higher growth of muscle cells means that the overall muscle mass increases, resulting in amplified strength.

One of the research involving mice with no myostatin recorded a 117% increase in muscle fibers. This means that follistatin 344 works to increase muscle mass in other ways as well.

The over-activity of myostatin can lead to a condition called skeletal muscle fibrosis (8). Follistatin 344 can eliminate the chances of developing this disorder.

Thus, the intake of follistatin 344 can build endurance and enhance the athletic capabilities of an individual.

Mice-based studies have shown a significant reduction in fat gain. This change can also be correlated to the ability of follistatin 344 to inhibit myostatin.

Follistatin 344 also delays the process of reproductive aging by binding to activin.

This glycoprotein also regulates the process of ovulation due to its interaction with granulosa cells to trigger the release of progesterone.

Biochemical analysis of seminal fluid suggests that it is rich in follistatin. Hence, intake of follistatin 344 can potentially increase fertility in individuals.

Perhaps, the most ground-breaking findings of mice-based studies suggest that follistatin 344 can help in some specific types of cancer treatment.

Some of the research suggests that follistatin 344 offers protection from breast cancer.

Another mice-based clinical study suggests that follistatin prevents the process of metastasis in lung and ovarian cancer.

It also provides quick yet effective recovery from tumor resection surgery of organs like the liver. 

One clinical trial involved injecting a single dose of follistatin 344. Surprisingly, the subjects developed dense hair growth. This means that thick and dense hair (higher follicle density) is one of the prospective benefits of follistatin 344 intakes.

Forms Of Follistatin 344

This protein cum hormone is mostly available in powdered and liquid forms, which needs to be prepared as described above.

The scientific reason why follistatin 344 isn’t available in the oral form is that some studies suggest that hormonal therapies are usually more effective when used in injectable form.

Follistatin 344 Side Effects

Studies focused on the follistatin 344 as a potential cancer treatment suggest that it negatively affects certain cancers such as prostate, esophagus, and skin (12). It does this by promoting the growth of these tumor cells.

Other side effects include the weakening of joints and ligaments. Some people who just started to use follistatin also reported increased body temperature upon their first administration.

You may also experience irritation and rashness at the injection site.

Follistatin 344 vs. Other Peptides

Follistatin 344 vs. IGF-1 LR3

IGF-1 LR3 works by making muscles more sensitive to insulin which results in the building of muscle tissues. Dosage guidelines are different for both peptides.

Although follistatin 344 works in a different way but both the proteins work towards achieving similar benefits. Thus, synergistic use is a go-to option!

Follistatin 344 vs. GHRP 6

GHRP 6 works by binding to growth hormone secretagogue receptors (GHSr) located in different body parts.

The frequency of intake is also one of the major differences between both peptides.

As the result of both the peptides is the same, stacking is the best way to move ahead.

Many of us wish that we could impress everyone we meet with our build, having enormous muscles, insane strength, and an overall husky appearance.

We tend to envision having the same figure as our fitness idols and one day surpassing their greatness.

While it isn’t possible for anyone to achieve this feat overnight, dedicated bodybuilders and elite-level athletes spend endless hours on high-intensity workouts and training to turn their dreams into a reality

In order to accelerate and enhance the process, many of these individuals look to the use of natural and synthetic peptides or proteins as they are well-researched and provide a safer alternative to the use of steroids.

One such protein that has great promise is Follistatin 344. Animal-based trials focused on this glycoprotein suggest that it significantly improves muscle growth and provides a realm of secondary benefits.

Stay with me till the end to decide whether or not you should use this glycoprotein as a part of your journey.

I’ll provide all of the facts, research, and personal reviews possible in order to help guide you in the right direction.

I’ll even provide my honest opinion at the end of this thread on Follistatin 344.

What Is Follistatin 344

Follistatin 344 is a recombinant form of naturally occurring follistatin. It comprises 323 Amino acids, and a carbohydrate chain is attached to its core, making it a naturally occurring glycoprotein.

Follistatin is a glycoprotein produced by folliculostellate cells (FS) located in the anterior pituitary gland and follows the autocrine signaling pathway.

Regarding the amino acids that make up follistatin 344, there is unusually high cysteine, a non-essential amino acid. Cysteine gives follistatin 344 its key characteristic property

How Does Follistatin Work

Follistatin 344 follows multiple courses of action to trigger specific changes in the body.

Myostatin, a growth and differentiation factor protein, is produced by myocytes (muscle cells). The primary function of myostatin is to act as a regulator by limiting the growth of muscles so that they don’t grow out of shape.

Follistatin 344 acts as a myostatin inhibitor. This subsequent blocking of myostatin by follistatin 344 leads to the suppression of myostatin activity. Thus, myostatin can’t act as a potent negative regulator of muscle growth.

Activin proteins enhance the secretion of follicle-stimulating hormone (FSH). However, in men, higher levels of follicle-stimulating hormone (FSH) limit muscle growth and cause abnormal testicle functioning.

Follistatin 344 inhibits the activin, which results in decreased secretion of the hormone.

Follistatin 344 acts on the granulosa cells to trigger the release of progesterone.  As progesterone is one of the main hormones regulating the menstrual cycle, slight fluctuations in the hormonal levels can disturb the whole cycle.

Although no human trials have confirmed these results, animal-based studies suggest that follistatin can reduce the life and growth of cancer cells and minimize the chances of metastasis.

Benefits Of Follistatin 344

The benefits of follistatin 344 can easily be predicted once you understand the mechanism of action that follistatin 344 follows.

Follistatin 344 inhibits the activity of myostatin which results in increased growth of muscle fibers in the body. Higher growth of muscle cells means that the overall muscle mass increases, resulting in amplified strength.

One of the research involving mice with no myostatin recorded a 117% increase in muscle fibers. This means that follistatin 344 works to increase muscle mass in other ways as well.

The over-activity of myostatin can lead to a condition called skeletal muscle fibrosis (8). Follistatin 344 can eliminate the chances of developing this disorder.

Thus, the intake of follistatin 344 can build endurance and enhance the athletic capabilities of an individual.

Mice-based studies have shown a significant reduction in fat gain. This change can also be correlated to the ability of follistatin 344 to inhibit myostatin.

Follistatin 344 also delays the process of reproductive aging by binding to activin.

This glycoprotein also regulates the process of ovulation due to its interaction with granulosa cells to trigger the release of progesterone.

Biochemical analysis of seminal fluid suggests that it is rich in follistatin. Hence, intake of follistatin 344 can potentially increase fertility in individuals.

Perhaps, the most ground-breaking findings of mice-based studies suggest that follistatin 344 can help in some specific types of cancer treatment.

Some of the research suggests that follistatin 344 offers protection from breast cancer.

Another mice-based clinical study suggests that follistatin prevents the process of metastasis in lung and ovarian cancer.

It also provides quick yet effective recovery from tumor resection surgery of organs like the liver. 

One clinical trial involved injecting a single dose of follistatin 344. Surprisingly, the subjects developed dense hair growth. This means that thick and dense hair (higher follicle density) is one of the prospective benefits of follistatin 344 intakes.

Forms Of Follistatin 344

This protein cum hormone is mostly available in powdered and liquid forms, which needs to be prepared as described above.

The scientific reason why follistatin 344 isn’t available in the oral form is that some studies suggest that hormonal therapies are usually more effective when used in injectable form.

Follistatin 344 Side Effects

Studies focused on the follistatin 344 as a potential cancer treatment suggest that it negatively affects certain cancers such as prostate, esophagus, and skin (12). It does this by promoting the growth of these tumor cells.

Other side effects include the weakening of joints and ligaments. Some people who just started to use follistatin also reported increased body temperature upon their first administration.

You may also experience irritation and rashness at the injection site.

Follistatin 344 vs. Other Peptides

Follistatin 344 vs. IGF-1 LR3

IGF-1 LR3 works by making muscles more sensitive to insulin which results in the building of muscle tissues. Dosage guidelines are different for both peptides.

Although follistatin 344 works in a different way but both the proteins work towards achieving similar benefits. Thus, synergistic use is a go-to option!

Follistatin 344 vs. GHRP 6

GHRP 6 works by binding to growth hormone secretagogue receptors (GHSr) located in different body parts.

The frequency of intake is also one of the major differences between both peptides.

As the result of both the peptides is the same, stacking is the best way to move ahead.